Immunomodulatory Potencies of Albino Rats Administered with Cinnamon (Cinnamomum zeylanicum) Bark Extract
DOI:
https://doi.org/10.67224/ioasdjmps.2025.v02i01.008Keywords:
Interleukin 6, Interleukin 6, CD4 + T cell, CD8 + T cell counts albino rats, Cinnamomum zeylanicum bark extractAbstract
The purpose of this study was to ascertain the impact of interleukin 6, CD4 + T cell, and CD8 + T cell counts in albino rats that were fed bark extract from Cinnamomum zeylanicum. Seven albino rats were randomly assigned to each of the two groups (n = 7); group 1, or Control (C), was fed only regular food. For 28 days, Group 2 received 20 mg/kg/day of bark leaf extract from Cinnamomum zeylanicum. The ELISA method was used to measure the level of Interleukin 6, and the flow cytometric approach was used to measure the levels of CD4 + T cells (μl/count) and CD8 + T cells (μl/count). Albino rats fed 20 mg/kg of bark extract of Cinnamomum zeylanicum bark had significantly higher levels of Interleukin 6, CD4 + T cell, and CD8 + T cell counts than the control group (P < 0.05). The higher levels of Interleukin 6, CD4 + T cells, and CD8 + T cells in albino rats fed bark extract from Cinnamomum zeylanicum may indicate that Interleukin 6 and immunological parameters are strengthened in albino rats. The aqueous cinnamon bark extracts successfully strengthen the immune system, it may be inferred.
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